The neurotoxic effect of long-term use of high-dose Pregabalin and the role of alpha tocopherol in amelioration: implication of MAPK signaling with oxidative stress and apoptosis

Pregabalin abuse has become an emerging concern; thus, the current study has been designed to study the neurotoxic hazards of prolonged high-dose of pregabalin (akin to that abused by addicts) and to evaluate the effect of alpha tocopherol as a possible ameliorating agent. The current study evaluated the brain neurotransmitters; dopamine, glutamate, and norepinephrine.

The study also assessed the expression of the apoptosis-related markers Bax, Bcl2, and caspase 3. Western-blotted analysis of the three major mitogen-activated protein kinases (MAPKs), the c-JUN N-terminal kinase (JNK), the p38 MAPK, and the extracellular signal-regulated kinase (ERK), has also been performed.

The study also evaluated oxidative stress via assessment of the cortical tissue levels of reduced glutathione and malondialdehyde and the activity of superoxide dismutase. Histopathological examination and histomorphometric evaluation of the darkly degenerated cortical neurons have also been performed. Pregabalin in high doses (150 mg/kg/day and 300 mg/kg/day) disrupted the ERK/JNK/p38-MAPK signaling, reversed the bax/bcl2 ratio, and induced oxidative stress.

AURION R-Gent SE-EM
500.044	Aurion	90 mL	Ask for price

AURION R-Gent SE-Intense
500.066	Aurion	60 mL	Ask for price

AURION R-Gent SE-Intense
500.077	Aurion	500 mL	Ask for price

AURION R-Gent SE-LM, replaced see 500.066
500.011	Aurion	60 mL	Ask for price

AURION R-Gent SE-LM, replaced see 500.077
500.022	Aurion	500 mL	Ask for price

LN-319
ABC-TC499S	AcceGen	1 vial	Ask for price
Description: Tissue: Brain. Tumorigenic.

AMG-319
204310	MedKoo Biosciences	10.0mg	EUR 190

(±)-SLV 319
B7689-10	ApexBio	10 mg	EUR 224.8
Description: GPCR/G protein|Cannabinoid Receptor

(±)-SLV 319
B7689-25	ApexBio	25mg	EUR 476
Description: GPCR/G protein|Cannabinoid Receptor

(±)-SLV 319
B7689-5	ApexBio	5 mg	EUR 131.2
Description: GPCR/G protein|Cannabinoid Receptor

(±)-SLV 319
B7689-50	ApexBio	50 mg	EUR 860
Description: GPCR/G protein|Cannabinoid Receptor

AMG-319
MBS130665-100mg	MyBiosource	100mg	EUR 1065

AMG-319
MBS130665-500mg	MyBiosource	500mg	EUR 2775

(+/-)-SLV 319
MBS133499-INQUIRE	MyBiosource	INQUIRE	Ask for price

LabMol-319
HY-150234	MedChemExpress	10 mg	EUR 270.57
Description: LabMol-319 is a potent zika virus (ZIKV) NS5 RdRp inhibitor with an IC50 of 1.6 μM. LabMol-319 is an antiviral agent[1].

ACP-319
MBS5779248-INQUIRE	MyBiosource	INQUIRE	Ask for price

ACP-319
T29615-10mg	TargetMol Chemicals	10mg	Ask for price
Description: ACP-319

ACP-319
T29615-1g	TargetMol Chemicals	1g	Ask for price
Description: ACP-319

ACP-319
T29615-1mg	TargetMol Chemicals	1mg	Ask for price
Description: ACP-319

ACP-319
T29615-50mg	TargetMol Chemicals	50mg	Ask for price
Description: ACP-319

ACP-319
T29615-5mg	TargetMol Chemicals	5mg	Ask for price
Description: ACP-319

MEF2A (Ab-319)
ANTY021040	Antagene	100ug	EUR 259

FKHR (Ab-319)
ANTY021161	Antagene	100ug	EUR 259

(S)-SLV 319
C3568-1	ApexBio	1 mg	EUR 88.8
Description: GPCR/G protein|Cannabinoid Receptor

(S)-SLV 319
C3568-10	ApexBio	10 mg	EUR 544
Description: GPCR/G protein|Cannabinoid Receptor

(S)-SLV 319
C3568-5	ApexBio	5 mg	EUR 347.2
Description: GPCR/G protein|Cannabinoid Receptor

(R)-SLV 319
C5122-1	ApexBio	1mg	EUR 92
Description: GPCR/G protein|Cannabinoid Receptor

(R)-SLV 319
C5122-10	ApexBio	10 mg	EUR 524
Description: GPCR/G protein|Cannabinoid Receptor

(R)-SLV 319
C5122-5	ApexBio	5 mg	EUR 348
Description: GPCR/G protein|Cannabinoid Receptor

(R)-SLV 319
C5122-50	ApexBio	50 mg	EUR 1490
Description: CB1 receptor antagonist

LN-319 cells
C0005001	Addexbio	One Frozen vial	EUR 620

IN-KT 319
I627990	Toronto Research Chemicals	100mg	EUR 9200
Description: 1374790-37-0

(R)-SLV 319
HY-121616	MedChemExpress	5mg	EUR 805.21
Description: (R)-SLV 319 is a potent and selective cannabinoid receptor 1 (CB1) antagonist with a Ki value of 894 nM. (R)-SLV 319 is a dextrorotatory counterpart of SLV 319[1]

LN-319 Cells
LN001	Neuromics	each	EUR 1069.2

(S)-SLV 319
S560015	Toronto Research Chemicals	50mg	EUR 9200
Description: 464213-10-3

(S)-SLV 319
T21914-10mg	TargetMol Chemicals	10mg	Ask for price
Description: (S)-SLV 319

(S)-SLV 319
T21914-1g	TargetMol Chemicals	1g	Ask for price
Description: (S)-SLV 319

(S)-SLV 319
T21914-1mg	TargetMol Chemicals	1mg	Ask for price
Description: (S)-SLV 319

(S)-SLV 319
T21914-50mg	TargetMol Chemicals	50mg	Ask for price
Description: (S)-SLV 319

(S)-SLV 319
T21914-5mg	TargetMol Chemicals	5mg	Ask for price
Description: (S)-SLV 319

(R)-SLV 319
T22140-10mg	TargetMol Chemicals	10mg	Ask for price
Description: (R)-SLV 319

(R)-SLV 319
T22140-1g	TargetMol Chemicals	1g	Ask for price
Description: (R)-SLV 319

(R)-SLV 319
T22140-1mg	TargetMol Chemicals	1mg	Ask for price
Description: (R)-SLV 319

(R)-SLV 319
T22140-50mg	TargetMol Chemicals	50mg	Ask for price
Description: (R)-SLV 319

(R)-SLV 319
T22140-5mg	TargetMol Chemicals	5mg	Ask for price
Description: (R)-SLV 319

(S)-SLV 319
TRC-S560015-50MG	Toronto Research Chemicals	50 mg	Ask for price

IN-KT 319
TRC-I627990-100MG	Toronto Research Chemicals	100 mg	Ask for price

LN-319 Cells
116213	Antibody Research Corporation	1 Vial	Ask for price

LN-319 Cells
116213L	Antibody Research Corporation	0.5 mg	Ask for price

LN-319 Cells
116213R	Antibody Research Corporation	100 µg	Ask for price

FKHR (Ab-319) Antibody
8B7086	AAT Bioquest	50ug	EUR 368
Description: FKHR (Ab-319) Antibody

MEF2A (Ab-319) Antibody
8B7145	AAT Bioquest	50ug	EUR 368
Description: MEF2A (Ab-319) Antibody

Influenza HA (307 - 319)
5-01389	CHI Scientific	4 x 5mg	EUR 294.84
Description: Pro-Lys-Tyr-Val-Lys-Gln-Asn-Thr-Leu-Lys-Leu-Ala-Thr

MEF2A (Ab-319) Antibody
21040	SAB	100ul	EUR 319

MEF2A (Ab-319) Antibody
21040-100ul	SAB	100ul	EUR 302.4

MEF2A (Ab-319) Antibody
21040-50ul	SAB	50ul	EUR 224.4

FKHR (Ab-319) Antibody
21161	SAB	100ul	EUR 319

FKHR (Ab-319) Antibody
21161-100ul	SAB	100ul	EUR 302.4

FKHR (Ab-319) Antibody
21161-50ul	SAB	50ul	EUR 224.4

MEF2A (Ab-319) Antibody
CSB-PA280396-	Cusabio	each	EUR 402
Description: A polyclonal antibody against MEF2A (Ab-319). Recognizes MEF2A (Ab-319) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

MEF2A (Ab-319) Antibody
CSB-PA280396-100ul	Cusabio	100ul	EUR 379.2
Description: A polyclonal antibody against MEF2A (Ab-319). Recognizes MEF2A (Ab-319) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

Zap-70 (Ab-319)
ANTY021173	Antagene	100ug	EUR 259

ZAP70 (Ab-319) Antibody
CSB-PA181899-	Cusabio	each	EUR 402
Description: A polyclonal antibody against ZAP70 (Ab-319). Recognizes ZAP70 (Ab-319) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

ZAP70 (Ab-319) Antibody
CSB-PA181899-100ul	Cusabio	100ul	EUR 379.2
Description: A polyclonal antibody against ZAP70 (Ab-319). Recognizes ZAP70 (Ab-319) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

FOXO1 (Ab-319) Antibody
CSB-PA953422-	Cusabio	each	EUR 402
Description: A polyclonal antibody against FOXO1 (Ab-319). Recognizes FOXO1 (Ab-319) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

FOXO1 (Ab-319) Antibody
CSB-PA953422-100ul	Cusabio	100ul	EUR 379.2
Description: A polyclonal antibody against FOXO1 (Ab-319). Recognizes FOXO1 (Ab-319) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

FKHR (Ab-319) Antibody
E11-7086B	EnoGene	100μg/100μl	EUR 225
Description: Available in various conjugation types.

MEF2A (Ab-319) Antibody
E11-7145B	EnoGene	100μg/100μl	EUR 225
Description: Available in various conjugation types.

MEF2A (Ab-319) Antibody
E021040-1	EnoGene	50μg/50μl	EUR 100
Description: Available in various conjugation types.

MEF2A (Ab-319) Antibody
E021040-2	EnoGene	100μg/100μl	EUR 170
Description: Available in various conjugation types.

FKHR (Ab-319) Antibody
E021161-1	EnoGene	50μg/50μl	EUR 100
Description: Available in various conjugation types.

FKHR (Ab-319) Antibody
E021161-2	EnoGene	100μg/100μl	EUR 170
Description: Available in various conjugation types.

SFXN1 (319) Mouse mAb
MBS435114-002mL	MyBiosource	0.02mL	EUR 270

SFXN1 (319) Mouse mAb
MBS435114-005mL	MyBiosource	0.05mL	EUR 415

SFXN1 (319) Mouse mAb
MBS435114-01mL	MyBiosource	0.1mL	EUR 660

SFXN1 (319) Mouse mAb
MBS435114-5x01mL	MyBiosource	5x0.1mL	EUR 2655

MEF2A (Ab-319) Antibody
MBS7130368-01mL	MyBiosource	0.1mL	EUR 270

MEF2A (Ab-319) Antibody
MBS7130368-5x01mL	MyBiosource	5x0.1mL	EUR 1200

Influenza HA (307-319)
MBS5789455-INQUIRE	MyBiosource	INQUIRE	Ask for price

FOXO1 (Ab-319) Antibody
MBS7131946-01mL	MyBiosource	0.1mL	EUR 270

FOXO1 (Ab-319) Antibody
MBS7131946-5x01mL	MyBiosource	5x0.1mL	EUR 1200

ZAP70 (Ab-319) Antibody
MBS7131951-01mL	MyBiosource	0.1mL	EUR 270

ZAP70 (Ab-319) Antibody
MBS7131951-5x01mL	MyBiosource	5x0.1mL	EUR 1200

Influenza HA (307-319)
MBS8246673-10mg	MyBiosource	10mg	EUR 600

Influenza HA (307-319)
MBS8246673-1mg	MyBiosource	1mg	EUR 235

Influenza HA (307-319)
MBS8246673-5mg	MyBiosource	5mg	EUR 430

Influenza HA (307-319)
MBS8246673-5x10mg	MyBiosource	5x10mg	EUR 2610

Beta-Amyloid (319-335)
MBS8246183-10mg	MyBiosource	10mg	EUR 625

Beta-Amyloid (319-335)
MBS8246183-1mg	MyBiosource	1mg	EUR 240

Beta-Amyloid (319-335)
MBS8246183-5mg	MyBiosource	5mg	EUR 445

Beta-Amyloid (319-335)
MBS8246183-5x10mg	MyBiosource	5x10mg	EUR 2730

FKHR (Ab-319) Antibody
MBS858928-01mg	MyBiosource	0.1mg	EUR 305

FKHR (Ab-319) Antibody
MBS858928-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

FKHR (Ab-319) Antibody
MBS858928-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

FKHR (Ab-319) Antibody
MBS858928-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

FKHR (Ab-319) Antibody
MBS858928-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

FKHR (Ab-319) Antibody
MBS857715-005mg	MyBiosource	0.05mg	EUR 190

FKHR (Ab-319) Antibody
MBS857715-01mg	MyBiosource	0.1mg	EUR 255

FKHR (Ab-319) Antibody
MBS857715-01mLAF405M	MyBiosource	0.1mL(AF405M)	EUR 465

FKHR (Ab-319) Antibody
MBS857715-01mLAF546	MyBiosource	0.1mL(AF546)	EUR 465

FKHR (Ab-319) Antibody
MBS857715-01mLAF750	MyBiosource	0.1mL(AF750)	EUR 465

MEF2A (Ab-319) Antibody
MBS8510197-01mg	MyBiosource	0.1mg	EUR 305

MEF2A (Ab-319) Antibody
MBS8510197-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

MEF2A (Ab-319) Antibody
MBS8510197-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

MEF2A (Ab-319) Antibody
MBS8510197-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

MEF2A (Ab-319) Antibody
MBS8510197-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

MEF2A (Ab-319) Antibody
MBS856735-005mg	MyBiosource	0.05mg	EUR 190

MEF2A (Ab-319) Antibody
MBS856735-01mg	MyBiosource	0.1mg	EUR 255

MEF2A (Ab-319) Antibody
MBS856735-01mLAF405M	MyBiosource	0.1mL(AF405M)	EUR 465

MEF2A (Ab-319) Antibody
MBS856735-01mLAF546	MyBiosource	0.1mL(AF546)	EUR 465

MEF2A (Ab-319) Antibody
MBS856735-01mLAF750	MyBiosource	0.1mL(AF750)	EUR 465

FKHR (Ab-319) Antibody
MBS9412592-005mL	MyBiosource	0.05mL	EUR 245

FKHR (Ab-319) Antibody
MBS9412592-01mL	MyBiosource	0.1mL	EUR 305

FKHR (Ab-319) Antibody
MBS9412592-5x01mL	MyBiosource	5x0.1mL	EUR 1230

MEF2A (Ab-319) Antibody
MBS9408672-005mL	MyBiosource	0.05mL	EUR 245

MEF2A (Ab-319) Antibody
MBS9408672-01mL	MyBiosource	0.1mL	EUR 305

MEF2A (Ab-319) Antibody
MBS9408672-5x01mL	MyBiosource	5x0.1mL	EUR 1230

Influenza HA (307-319)
TP1854-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Influenza HA (307-319)

Influenza HA (307-319)
TP1854-1g	TargetMol Chemicals	1g	Ask for price
Description: Influenza HA (307-319)

Influenza HA (307-319)
TP1854-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Influenza HA (307-319)

Influenza HA (307-319)
TP1854-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Influenza HA (307-319)

Influenza HA (307-319)
TP1854-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Influenza HA (307-319)

anti-FOXO1A (Ab-319)
LF-PA20163	Abfrontier	100 ul	EUR 400.8
Description: Rabbit polyclonal to FOXO1A

anti-MEF2A (Ab-319)
LF-PA20283	Abfrontier	100 ul	EUR 400.8
Description: Rabbit polyclonal to MEF2A

anti-ZAP70 (Ab-319)
LF-PA20528	Abfrontier	100 ul	EUR 400.8
Description: Rabbit polyclonal to ZAP70

GPR-99 (319-337) (Human)
001-31	PHOENIX PEPTIDE	100 μg	EUR 177.12

GPR-8 (319-333) (Human)
001-57	PHOENIX PEPTIDE	100 μg	EUR 214.92

ZAP-70 (Ab-319) Antibody
8B7255	AAT Bioquest	50ug	EUR 368
Description: ZAP-70 (Ab-319) Antibody

Zap-70 (Ab-319) Antibody
21173	SAB	100ul	EUR 319

Zap-70 (Ab-319) Antibody
21173-100ul	SAB	100ul	EUR 302.4

Zap-70 (Ab-319) Antibody
21173-50ul	SAB	50ul	EUR 224.4

Polyclonal HSF1 Antibody (aa270-319)
APR07827G	Leading Biology	0.05ml	EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HSF1 (aa270-319). This antibody is tested and proven to work in the following applications:

Yeast Reductase (aa 1 - 319)
DAG1754	Creative Diagnostics	500 ug	EUR 756
Description: Recombinant

Influenza HA (307 319) Peptide
20-abx266401	Abbexa	Ask for price Ask for price Ask for price	5 mg 10 mg 25 mg

Influenza HA (307 319) Peptide
abx266401-1ml	Abbexa	1 ml	EUR 487.5

Influenza HA (307 319) Peptide
abx266401-200l	Abbexa	200 µl	EUR 337.5

Rabbit anti FKHR (Ab-319)
AP21161	Angio Proteomie	100ul	EUR 307.2

Rabbit anti Zap70 (Ab-319)
AP21173	Angio Proteomie	100ul	EUR 307.2

ZAP-70 (Ab-319) Antibody
E11-7255B	EnoGene	100μg	EUR 225
Description: Available in various conjugation types.

Zap-70 (Ab-319) Antibody
E021173-1	EnoGene	50μg/50μl	EUR 100
Description: Available in various conjugation types.

Zap-70 (Ab-319) Antibody
E021173-2	EnoGene	100μg/100μl	EUR 170
Description: Available in various conjugation types.

Anti-HIV1 Vif Antibody (319)
MBS4160979-01mL	MyBiosource	0.1mL	EUR 820

Anti-HIV1 Vif Antibody (319)
MBS4160979-5x01mL	MyBiosource	5x0.1mL	EUR 3430

Mouse Anti-HIV1 Vif [319]
MBS375252-01mg	MyBiosource	0.1mg	EUR 520

Mouse Anti-HIV1 Vif [319]
MBS375252-5x01mg	MyBiosource	5x0.1mg	EUR 2125

ZAP-70 (Ab-319) Antibody
MBS858463-01mg	MyBiosource	0.1mg	EUR 305

ZAP-70 (Ab-319) Antibody
MBS858463-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

ZAP-70 (Ab-319) Antibody
MBS858463-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

ZAP-70 (Ab-319) Antibody
MBS858463-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

ZAP-70 (Ab-319) Antibody
MBS858463-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

Zap-70 (Ab-319) Antibody
MBS856963-005mg	MyBiosource	0.05mg	EUR 190

Zap-70 (Ab-319) Antibody
MBS856963-01mg	MyBiosource	0.1mg	EUR 255

Zap-70 (Ab-319) Antibody
MBS856963-01mLAF405M	MyBiosource	0.1mL(AF405M)	EUR 465

Zap-70 (Ab-319) Antibody
MBS856963-01mLAF546	MyBiosource	0.1mL(AF546)	EUR 465

Zap-70 (Ab-319) Antibody
MBS856963-01mLAF750	MyBiosource	0.1mL(AF750)	EUR 465

Zap-70 (Ab-319) Antibody
MBS9407499-005mL	MyBiosource	0.05mL	EUR 245

Zap-70 (Ab-319) Antibody
MBS9407499-01mL	MyBiosource	0.1mL	EUR 305

Zap-70 (Ab-319) Antibody
MBS9407499-5x01mL	MyBiosource	5x0.1mL	EUR 1230

pcDNA3.1(+)-Flag-CTBP11(319-440AA)
PPL00276-2e	Bioworld Biotech	366bp	EUR 218
Description: pcDNA3.1(+)

CoV-2 S1 (319-541)
sars-021	ProSpec Tany	2µg	EUR 60
Description: Recombinant Coronavirus 2019-nCoV Spike Glycoprotein-S1 Receptor Binding Domain (319-541 a.a.)

CoV-2 S1 (319-537)
sars-038	ProSpec Tany	2µg	EUR 100
Description: Recombinant Coronavirus 2019-nCoV Spike Glycoprotein-S1 Receptor Binding Domain (319-537 a.a.)

CoV-2 S1 (319-529)
sars-050	ProSpec Tany	2µg	EUR 60
Description: Recombinant Coronavirus 2019-nCoV Spike Glycoprotein-S1 Receptor Binding Domain (319-529 a.a.)

Anti-MEF2A (Ab-319) Antibody
Y021040	ABM	100 µg	EUR 285

Anti-FKHR (Ab-319) Antibody
Y021161	ABM	100 µg	EUR 285

Influenza HA (307-319) Peptide
PE-53126	Novatein Biosciences, Inc.	Ask for price Ask for price Ask for price	1 mg 5 mg 10 mg

GPR-41 (292-319) (Rat, Mouse)
001-98	PHOENIX PEPTIDE	100 μg	EUR 282.96

Anti-Zap-70 (Ab-319) Antibody
A00754	BosterBio	100ul	EUR 360
Description: Boster Bio Anti-Zap-70 (Ab-319) Antibody (Catalog # A00754). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Zinc Finger Protein 319 (ZNF319) Antibody
abx030177-400l	Abbexa	400 µl	EUR 518.75

Zinc Finger Protein 319 (ZNF319) Antibody
abx030177-400ul	Abbexa	400 ul	EUR 627.6

Zinc Finger Protein 319 (ZNF319) Antibody
abx030177-80l	Abbexa	80 µl	EUR 281.25

Zap-70 (Ab-319) Conjugated Antibody
C21173	SAB	100ul	EUR 476.4

CDDO EA, RTA 405, tP 319
MBS130347-100mg	MyBiosource	100mg	EUR 1065

CDDO EA, RTA 405, tP 319
MBS130347-500mg	MyBiosource	500mg	EUR 2775

OAEC00390-50UG - MEF2A (Ab-319) Antibody
OAEC00390-50UG	Aviva Systems Biology	50ug	EUR 259

OAEC00506-50UG - FKHR (Ab-319) Antibody
OAEC00506-50UG	Aviva Systems Biology	50ug	EUR 259

Zap-70 (Ab-319) Conjugated Antibody
MBS9438734-01mLAF350	MyBiosource	0.1mL(AF350)	EUR 480

Zap-70 (Ab-319) Conjugated Antibody
MBS9438734-01mLAF405	MyBiosource	0.1mL(AF405)	EUR 480

Zap-70 (Ab-319) Conjugated Antibody
MBS9438734-01mLAF488	MyBiosource	0.1mL(AF488)	EUR 480

Zap-70 (Ab-319) Conjugated Antibody
MBS9438734-01mLAF555	MyBiosource	0.1mL(AF555)	EUR 480

Zap-70 (Ab-319) Conjugated Antibody
MBS9438734-01mLBiotin	MyBiosource	0.1mL(Biotin)	EUR 480

CoV-2 S1 (319-541), Fc
sars-029	ProSpec Tany	2µg	EUR 100
Description: Recombinant Coronavirus 2019-nCoV Spike Glycoprotein-S1 Receptor Binding Domain (319-541 a.a.), Fc

It also diminished the release of dopamine, glutamate, and norepinephrine and increased the count of degenerated neurons. Alpha tocopherol treatment significantly attenuated the deleterious effects induced by pregabalin. The role of alpha tocopherol in ameliorating the oxidative stress injury, and apoptosis induced by pregabalin, along with its role in normalizing neurotransmitters, modulating the ERK/JNK/p38-MAPK signaling pathways and improving the histopathological cortical changes, offers alpha tocopherol as a promising adjunctive therapy in patients undergoing prolonged pregabalin therapy as those suffering from prolonged seizures and neuropathies.