Apoptosis repressor with caspase recruitment domain (ARC) is a extremely efficient and multifunctional inhibitor of apoptosis that’s primarily expressed in postmitotic cells similar to cardiomyocytes and skeletal muscle cells. ARC incorporates a C-terminal area wealthy in proline and glutamic acid residues and an N-terminal caspase recruitment domain (CARD). The CARD is initially described as a protein-binding motif that interacts with caspase via a CARD-CARD interplay. Initially, the inhibitory impact of ARC was solely discovered in apoptosis, nevertheless, it was later discovered that ARC additionally performed a regulatory position in different varieties of cell death.
As a robust cardioprotective issue, ARC can defend the center by inhibiting the death of cardiomyocytes in varied methods. ARC can scale back the cardiomyocyte apoptotic response to varied stresses and accidents, together with extrinsic apoptosis induced by death receptor ligands, mobile Ca2+ homeostasis and the dysregulation of endoplasmic reticulum (ER) stress, oxidative stress and hypoxia. In addition, adjustments in ARC transcription and translation ranges in the center may cause a collection of physiological and pathological adjustments, and ARC can even carry out corresponding capabilities via interactions with different molecules.
Although there was a lot analysis on ARC, the practical redundancy amongst proteins reveals that ARC nonetheless has a lot analysis worth. This overview summarizes the molecular traits of ARC, its roles in the assorted death modes in cardiomyocytes and the roles of ARC in cardiac pathophysiology. This article additionally describes the potential therapeutic impact and analysis prospects of ARC. ARC was overexpressed in the nuclei and cytoplasm of most FAP adenomas investigated. Cytoplasmic ARC staining was reasonably stronger (rating 2) in 49.1% and considerably stronger (rating 3) in 32.5% of adenomas in comparison with non-tumorous colorectal mucosa.
In 18.4% (n = 39/212) of adenomas, cytoplasmic ARC staining was equal to that in non-tumorous mucosa. Nuclear expression of ARC in over 75% of cells was current in 30.7% of investigated adenomas, and nuclear expression in 10-75% of cells was detected in 62.7%. ARC expression in underneath 10% of nuclei was discovered in 6.6% of adenomas. The correlation between nuclear ARC expression and cytoplasmic ARC expression was extremely important. Moreover, nuclear ARC expression correlated positively with overexpression of Bcl-2, COX-2 p53 and β-catenin. Cytoplasmic ARC additionally correlated with overexpression of Bcl-2. Sporadic MMR deficiency was detected in only a few FAP adenomas and confirmed no correlation with nuclear or cytoplasmic ARC.
Lactonic sophorolipid-induced apoptosis in human HepG2 cells via the Caspase-Three pathway
Liver most cancers, one of the commonest varieties of most cancers in the world, is the second main trigger of death for most cancers sufferers. For liver most cancers, there may be an pressing want for an efficient remedy with no or much less poisonous unwanted effects. Lactonic sophorolipids (LSL), as a possible anticancer drug, has attracted vast consideration of pharmaceutical researchers with its good organic actions. The results of LSL and cell death inhibitors had been measured by MTT take a look at on HepG2 cells. Meanwhile, the morphology of the cells was noticed underneath a microscope.
The apoptosis charge was detected by movement cytometry, and the expression ranges of enzyme exercise of Caspase-3 and Caspase-9 had been measured by detection kits. Meanwhile, mRNA ranges of Apaf-1, Caspase-3, Bax, and Bcl-2 had been measured by quantitative real-time RT-PCR; protein ranges of Caspase-3, Cleaved Caspase-3, Bax, and Bcl-2 had been measured by western blot. LSL can inhibit the proliferation of cells, and it’s potential to induce apoptosis in cells. The HepG2 cells with LSL co-culture exhibited typical apoptotic morphology, and the expression ranges of enzyme exercise of Caspase-3 and Caspase-9 elevated (P< 0.05).
We additionally discovered that LSL will increase cell apoptosis charge and regulates the expression of genes and proteins related with apoptosis via the Caspase-Three pathway. These outcomes point out that LSL could also be one of the potential drug candidates to inhibit the proliferation and induce apoptosis in HepG2 cells.Key factors• LSL, which is of good organic actions similar to anti-bacterium, virus elimination, and inflammatory response elimination, has been firstly used to intervene in vitro to analyze its impact on HepG2 cell proliferation.• LSL can inhibit the proliferation of cells, and it’s potential to induce apoptosis in HepG2 cells via the Caspase-Three pathway.• The mechanism of LSL motion on HepG2 cell proliferation was firstly additionally mentioned, which supplies a sure experimental reference for the medical remedy of liver most cancers.
Regulation of docosahexaenoic acid-induced apoptosis of confluent endothelial cells: Contributions of MAPKs and caspases
Endothelial cells, which assist to take care of vascular homeostasis, will be functionally modulated by polyunsaturated fatty acids. Previously, we reported that docosahexaenoic acid (DHA) lowered the viability of confluent EA.hy926 endothelial cells with caspase-Three activation. This examine subsequently examined the molecular mechanism by which DHA impacts the viability of confluent cells, with a concentrate on the interplay between caspase-9, caspase-8, caspase-3, p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal kinase (JNK) by Western blotting.
Annexin V-PE Apoptosis Detection Kit - 100 assays |
GWB-AXR090 |
GenWay Biotech |
100 assays |
Ask for price |
Annexin V-PE Apoptosis Detection Kit - 25 assays |
GWB-AXR091 |
GenWay Biotech |
25 assays |
Ask for price |
Annexin V-PE-Cy5 Apoptosis Detection Kit - 100 assays |
GWB-AXR093 |
GenWay Biotech |
100 assays |
Ask for price |
Annexin V-PE-Cy5 Apoptosis Detection Kit - 25 assays |
GWB-AXR094 |
GenWay Biotech |
25 assays |
Ask for price |
Annexin V Apoptosis Detection Kit (PE) |
abx290003-100test |
Abbexa |
100 test |
EUR 693.6 |
|
Annexin V Apoptosis Detection Kit (PE) |
abx290015-200test |
Abbexa |
200 test |
EUR 644.4 |
|
Annexin V Apoptosis Detection Kit (PE) |
55R-1288 |
Fitzgerald |
25 assays |
EUR 553 |
|
Description: Annexin V Apoptosis Kit for detection of apoptosis in the research laboratory |
Annexin V-PE Apoptosis Detection Kit |
K128-100 |
Biovision |
each |
EUR 601.2 |
Annexin V-PE Apoptosis Detection Kit |
K128-25 |
Biovision |
each |
EUR 248.4 |
Annexin V-PE Apoptosis Detection Kit |
K128-400 |
Biovision |
each |
EUR 1149.6 |
Annexin V-PE Apoptosis Detection Kit |
K2200-100 |
ApexBio |
100 assays |
EUR 398 |
Description: Detects Apoptosis in Live Cells within 10 min |
Annexin V-PE Apoptosis Detection Kit |
K2200-25 |
ApexBio |
25 assays |
EUR 285.6 |
Annexin V-PE Apoptosis Detection Kit |
K2200-400 |
ApexBio |
400 assays |
EUR 1336.8 |
Annexin V Apoptosis Detection Kit (PE) (CY5) |
55R-1289 |
Fitzgerald |
25 assays |
EUR 540 |
|
Description: Annexin V Apoptosis Kit for detection of apoptosis in the research laboratory |
Annexin V Apoptosis Detection Kit Plus (PE) |
55R-1304 |
Fitzgerald |
25 assays |
EUR 533 |
|
Description: Annexin V Apoptosis Kit for detection of apoptosis in the research laboratory |
Annexin V / 7AAD Apoptosis Detection Kit (PE) |
abx290009-100test |
Abbexa |
100 test |
EUR 594 |
|
Annexin V Apoptosis Detection Kit : PE (OKTA00005) |
OKTA00005 |
Aviva Systems Biology |
KIT |
EUR 364.8 |
Description: Description of target: ;Species reactivity: ;Application: FC;Assay info: ;Sensitivity: |
Annexin V-PE-Cy5 Apoptosis Detection Kit |
K129-100 |
Biovision |
each |
EUR 588 |
Annexin V-PE-Cy5 Apoptosis Detection Kit |
K129-25 |
Biovision |
each |
EUR 301.2 |
Annexin V-PE-Cy5 Apoptosis Detection Kit |
K129-400 |
Biovision |
each |
EUR 1246.8 |
Annexin V-PE-Cy5 Apoptosis Detection Kit |
K2201-100 |
ApexBio |
100 assays |
EUR 643 |
Description: Detects Apoptosis in Live Cells within 10 min |
Annexin V-PE-Cy5 Apoptosis Detection Kit |
K2201-25 |
ApexBio |
25 assays |
EUR 351.6 |
Annexin V-PE-Cy5 Apoptosis Detection Kit |
K2201-400 |
ApexBio |
400 assays |
EUR 1503.6 |
Annexin V (PE) / 7-AAD Apoptosis Detection Kit (PE) |
abx090609-100tests |
Abbexa |
100 tests |
EUR 718.8 |
|
Annexin V Apoptosis Detection Kit (CY3) |
55R-1266 |
Fitzgerald |
25 assays |
EUR 547 |
|
Description: Annexin V Apoptosis Kit for detection of apoptosis in the research laboratory |
Annexin V Apoptosis Detection Kit (CY5) |
55R-1267 |
Fitzgerald |
25 assays |
EUR 567 |
|
Description: Annexin V Apoptosis Kit for detection of apoptosis in the research laboratory |
Annexin V Apoptosis Detection Kit (FITC) |
abx290002-100test |
Abbexa |
100 test |
EUR 644.4 |
|
Annexin V Apoptosis Detection Kit (FITC) |
abx290014-200test |
Abbexa |
200 test |
EUR 577.2 |
|
Annexin V Apoptosis Detection Kit (FITC) |
55R-1265 |
Fitzgerald |
25 assays |
EUR 567 |
|
Description: Annexin V Apoptosis Kit for detection of apoptosis in the research laboratory |
Annexin V-PE/7-AAD Apoptosis Detection Kit |
DLSM0246 |
DL Develop |
100 Assays |
Ask for price |
Description: Detection phosphatidylserine on the outer leaflet of the cell membrane using flow cytometry. |
Annexin V-PE/7-AAD Apoptosis Detection Kit |
E28LS4004-100 |
EnoGene |
100T |
EUR 793.65 |
Annexin V-PE/7-AAD Apoptosis Detection Kit |
E28LS4004-20 |
EnoGene |
20T |
EUR 279.37 |
Annexin V-PE/7-AAD Apoptosis Detection Kit |
E28LS4004-50 |
EnoGene |
50T |
EUR 507.94 |
Annexin V-PE/7-AAD Apoptosis Detection Kit |
A213-01 |
Vazyme |
50 rxn |
EUR 96.5 |
Annexin V-PE/7-AAD Apoptosis Detection Kit |
A213-02 |
Vazyme |
100 rxn |
EUR 145 |
Annexin V Apoptosis Detection Kit (Biotin) |
abx290017-200test |
Abbexa |
200 test |
EUR 744 |
|
Annexin V Apoptosis Detection Kit (biotin) |
55R-1271 |
Fitzgerald |
25 assays |
EUR 513 |
|
Description: Annexin V Apoptosis Kit for detection of apoptosis in the research laboratory |
Annexin V EGFP Apoptosis Detection Kit |
55R-1268 |
Fitzgerald |
25 assays |
EUR 513 |
|
Description: Annexin V Apoptosis Kit for detection of apoptosis in the research laboratory |
Annexin V-EGFP Apoptosis Detection Kit |
EBA1250 |
EnoGene |
50T |
EUR 150 |
Annexin V / PI Apoptosis Detection Kit (FITC) |
abx290007-100test |
Abbexa |
100 test |
EUR 543.6 |
|
Annexin V Apoptosis Detection Kit Plus (CY3) |
55R-1303 |
Fitzgerald |
25 assays |
EUR 540 |
|
Description: Annexin V Apoptosis Kit for detection of apoptosis in the research laboratory |
Annexin V / PI Apoptosis Detection Kit (Biotin) |
abx290011-100test |
Abbexa |
100 test |
EUR 744 |
|
Annexin V Apoptosis Detection Kit (CF-Blue) |
abx290018-200test |
Abbexa |
200 test |
EUR 744 |
|
Annexin V Apoptosis Detection Kit Plus (FITC) |
55R-1302 |
Fitzgerald |
25 assays |
EUR 547 |
|
Description: Annexin V Apoptosis Kit for detection of apoptosis in the research laboratory |
Annexin V Apoptosis Detection Kit (Dylight 634) |
abx290016-200test |
Abbexa |
200 test |
EUR 644.4 |
|
Annexin V (APC) / PI Apoptosis Detection Kit |
abx090605-100l |
Abbexa |
100 µl |
EUR 562.5 |
Annexin V (APC) / PI Apoptosis Detection Kit |
abx090605-1ml |
Abbexa |
1 ml |
Ask for price |
Annexin V (APC) / PI Apoptosis Detection Kit |
abx090605-200l |
Abbexa |
200 µl |
Ask for price |
Annexin V (FITC) / PI Apoptosis Detection Kit |
abx090601-100tests |
Abbexa |
100 tests |
EUR 552 |
|
Annexin V Apoptosis Detection Kit : APC (OKTA00002) |
OKTA00002 |
Aviva Systems Biology |
KIT |
EUR 396 |
Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity: |
Annexin V-FITC/PI Apoptosis Detection Kit |
DLSM0242 |
DL Develop |
100 Assays |
Ask for price |
Description: Detection phosphatidylserine on the outer leaflet of the cell membrane using flow cytometry. |
Annexin V-eGFP/PI Apoptosis Detection Kit |
DLSM0243 |
DL Develop |
100 Assays |
Ask for price |
Description: Detection phosphatidylserine on the outer leaflet of the cell membrane using flow cytometry. |
Annexin V-FITC/PI Apoptosis Detection Kit |
E28LS4000-100 |
EnoGene |
100T |
EUR 698.41 |
Annexin V-FITC/PI Apoptosis Detection Kit |
E28LS4000-20 |
EnoGene |
20T |
EUR 279.37 |
Annexin V-FITC/PI Apoptosis Detection Kit |
E28LS4000-50 |
EnoGene |
50T |
EUR 469.84 |
Annexin V-eGFP/PI Apoptosis Detection Kit |
E28LS4003-100 |
EnoGene |
100T |
EUR 793.65 |
Annexin V-eGFP/PI Apoptosis Detection Kit |
E28LS4003-20 |
EnoGene |
20T |
EUR 279.37 |
Annexin V-eGFP/PI Apoptosis Detection Kit |
E28LS4003-50 |
EnoGene |
50T |
EUR 507.94 |
Annexin V-FITC/PI Apoptosis Detection Kit |
A211-01 |
Vazyme |
50 rxn |
EUR 73.21 |
Annexin V-FITC/PI Apoptosis Detection Kit |
A211-02 |
Vazyme |
100 rxn |
EUR 123 |
Annexin V-EGFP/PI Apoptosis Detection kit |
KTA0005-100T |
Abbkine |
100 T |
EUR 169 |
Description: Abbkine Annexin V-EGFP/PI Apoptosis Detection kit allows the discrimination of intact cells, early apoptotic and late apoptotic or necrotic cells. |
Annexin V-EGFP/PI Apoptosis Detection kit |
KTA0005-20T |
Abbkine |
20 T |
EUR 49 |
Description: Abbkine Annexin V-EGFP/PI Apoptosis Detection kit allows the discrimination of intact cells, early apoptotic and late apoptotic or necrotic cells. |
Annexin V-EGFP/PI Apoptosis Detection kit |
KTA0005-50T |
Abbkine |
50 T |
EUR 99 |
Description: Abbkine Annexin V-EGFP/PI Apoptosis Detection kit allows the discrimination of intact cells, early apoptotic and late apoptotic or necrotic cells. |
Annexin V Apoptosis Detection Kit : FITC (OKTA00003) |
OKTA00003 |
Aviva Systems Biology |
KIT |
EUR 380.4 |
Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity: |
Annexin V / 7ADD Apoptosis Detection Kit (FITC) |
abx290008-100test |
Abbexa |
100 test |
EUR 543.6 |
|
Annexin V / PI Apoptosis Detection Kit (CF-Blue) |
abx290012-100test |
Abbexa |
100 test |
EUR 678 |
|
Annexin V / PI Apoptosis Detection Kit (Dylight 634) |
abx290010-100test |
Abbexa |
100 test |
EUR 644.4 |
|
Annexin V (APC) / PI Apoptosis Detection Kit (APC) |
abx090605-100tests |
Abbexa |
100 tests |
EUR 777.6 |
|
Annexin V (APC) / 7-AAD Apoptosis Detection Kit |
abx090607-100l |
Abbexa |
100 µl |
EUR 587.5 |
Annexin V (APC) / 7-AAD Apoptosis Detection Kit |
abx090607-1ml |
Abbexa |
1 ml |
Ask for price |
Annexin V (APC) / 7-AAD Apoptosis Detection Kit |
abx090607-200l |
Abbexa |
200 µl |
Ask for price |
Annexin V (FITC) / 7-AAD Apoptosis Detection Kit |
abx090603-100tests |
Abbexa |
100 tests |
EUR 594 |
|
Annexin V-FITC / PI Cell Apoptosis Detection Kit |
20-abx098246 |
Abbexa |
-
Ask for price
-
Ask for price
|
|
|
Annexin V-EGFP / PI Cell Apoptosis Detection Kit |
20-abx098247 |
Abbexa |
-
Ask for price
-
Ask for price
|
|
|
Annexin V-EGFP / PI Cell Apoptosis Detection Kit |
abx098247-100l |
Abbexa |
100 µl |
EUR 300 |
Annexin V-EGFP / PI Cell Apoptosis Detection Kit |
abx098247-1ml |
Abbexa |
1 ml |
Ask for price |
Annexin V-EGFP / PI Cell Apoptosis Detection Kit |
abx098247-200l |
Abbexa |
200 µl |
EUR 387.5 |
Annexin V / 7AAD Apoptosis Detection Kit (CF-Blue) |
abx290013-100test |
Abbexa |
100 test |
EUR 678 |
|
Annexin Ⅴ-633 Apoptosis Detection Kit |
18146-44 |
NACALAI TESQUE |
100TESTS |
EUR 350 |
OKTA00002-1KIT - Annexin V Apoptosis Detection Kit : APC |
OKTA00002-1KIT |
Aviva Systems Biology |
KIT |
EUR 279 |
|
OKTA00003-1KIT - Annexin V Apoptosis Detection Kit : FITC |
OKTA00003-1KIT |
Aviva Systems Biology |
KIT |
EUR 269 |
|
Annexin V (APC) / 7-AAD Apoptosis Detection Kit (APC) |
abx090607-100tests |
Abbexa |
100 tests |
EUR 811.2 |
|
Annexin V-Alexa Fluor488/PI Apoptosis Detection Kit |
E28LS4001-100 |
EnoGene |
100T |
EUR 793.65 |
Annexin V-Alexa Fluor488/PI Apoptosis Detection Kit |
E28LS4001-20 |
EnoGene |
20T |
EUR 279.37 |
Annexin V-Alexa Fluor488/PI Apoptosis Detection Kit |
E28LS4001-50 |
EnoGene |
50T |
EUR 507.94 |
Annexin V-Alexa Fluor647/PI Apoptosis Detection Kit |
E28LS4002-100 |
EnoGene |
100T |
EUR 793.65 |
Annexin V-Alexa Fluor647/PI Apoptosis Detection Kit |
E28LS4002-20 |
EnoGene |
20T |
EUR 279.37 |
Annexin V-Alexa Fluor647/PI Apoptosis Detection Kit |
E28LS4002-50 |
EnoGene |
50T |
EUR 507.94 |
Annexin V-AbFluor™ 488/PI Apoptosis Detection kit |
KTA0002-100T |
Abbkine |
100 T |
EUR 179 |
Description: Abbkine Annexin V-AbFluor™ 488/PI Apoptosis Detection kit allows the discrimination of intact cells, early apoptotic and late apoptotic or necrotic cells. |
Annexin V-AbFluor™ 488/PI Apoptosis Detection kit |
KTA0002-50T |
Abbkine |
50 T |
EUR 109 |
Description: Abbkine Annexin V-AbFluor™ 488/PI Apoptosis Detection kit allows the discrimination of intact cells, early apoptotic and late apoptotic or necrotic cells. |
Annexin V-AbFluor™ 488/PI Apoptosis Detection kit |
KTA0002-each |
Abbkine |
each |
Ask for price |
Annexin V-Alexa Fluor 488/PI Apoptosis Detection Kit |
DLSM0244 |
DL Develop |
100 Assays |
Ask for price |
Description: Detection phosphatidylserine on the outer leaflet of the cell membrane using flow cytometry. |
Annexin V-Alexa Fluor 647/PI Apoptosis Detection Kit |
DLSM0245 |
DL Develop |
100 Assays |
Ask for price |
Description: Detection phosphatidylserine on the outer leaflet of the cell membrane using flow cytometry. |
Annexin V-PE Apoptosis Kit Plus - 400 assays |
GWB-AXR158 |
GenWay Biotech |
400 assays |
Ask for price |
Annexin Ⅴ-FITC Apoptosis Detection Kit |
15342-54 |
NACALAI TESQUE |
100TESTS |
EUR 350 |
Annexin V-Cy3 Apoptosis Kit - 400 assays |
GWB-AXR006 |
GenWay Biotech |
400 assays |
Ask for price |
Annexin V-Cy5 Apoptosis Kit - 400 assays |
GWB-AXR009 |
GenWay Biotech |
400 assays |
Ask for price |
Annexin V-FITC Apoptosis Kit - 400 assays |
GWB-AXR003 |
GenWay Biotech |
400 assays |
Ask for price |
Annexin V-EGFP Apoptosis Kit - 400 assays |
GWB-AXR012 |
GenWay Biotech |
400 assays |
Ask for price |
Annexin V-iFluor 488 + PI Apoptosis Detection Reagent |
E34M001D |
EnoGene |
50 rxn |
EUR 225 |
Annexin V-Biotin Apoptosis Kit - 400 assays |
GWB-AXR023 |
GenWay Biotech |
400 assays |
Ask for price |
Annexin V-AbFluor™ 647 Apoptosis Detection kit (Red Fluorescence) |
KTA0004-100T |
Abbkine |
100 T |
EUR 269 |
Description: Abbkine Annexin V-AbFluor™ 647 Apoptosis Detection Kit allows the discrimination of intact cells, early apoptotic and late apoptotic or necrotic cells. |
Annexin V-AbFluor™ 647 Apoptosis Detection kit (Red Fluorescence) |
KTA0004-50T |
Abbkine |
50 T |
EUR 159 |
Description: Abbkine Annexin V-AbFluor™ 647 Apoptosis Detection Kit allows the discrimination of intact cells, early apoptotic and late apoptotic or necrotic cells. |
Annexin V-AbFluor™ 647 Apoptosis Detection kit (Red Fluorescence) |
KTA0004-each |
Abbkine |
each |
Ask for price |
Annexin V-AbFluor™ 405 Apoptosis Detection kit (Blue Fluorescence) |
KTA0001-100T |
Abbkine |
100 T |
EUR 269 |
Description: Abbkine Annexin V-AbFluor™ 405 Apoptosis Detection Kit allows the discrimination of intact cells, early apoptotic and late apoptotic or necrotic cells. |
Annexin V-AbFluor™ 405 Apoptosis Detection kit (Blue Fluorescence) |
KTA0001-50T |
Abbkine |
50 T |
EUR 159 |
Description: Abbkine Annexin V-AbFluor™ 405 Apoptosis Detection Kit allows the discrimination of intact cells, early apoptotic and late apoptotic or necrotic cells. |
Annexin V-AbFluor™ 405 Apoptosis Detection kit (Blue Fluorescence) |
KTA0001-each |
Abbkine |
each |
Ask for price |
Annexin V-AbFluor™ 555 Apoptosis Detection kit (Orange Fluorescence) |
KTA0003-100T |
Abbkine |
100 T |
EUR 269 |
Description: Annexin V-AbFluor™ 555 Apoptosis Detection Kit allows the identification and quantification of apoptotic cells. |
Annexin V-AbFluor™ 555 Apoptosis Detection kit (Orange Fluorescence) |
KTA0003-50T |
Abbkine |
50 T |
EUR 159 |
Description: Annexin V-AbFluor™ 555 Apoptosis Detection Kit allows the identification and quantification of apoptotic cells. |
Annexin V-AbFluor™ 555 Apoptosis Detection kit (Orange Fluorescence) |
KTA0003-each |
Abbkine |
each |
Ask for price |
Annexin V-Cy3 Apoptosis Kit Plus - 400 assays |
GWB-AXR155 |
GenWay Biotech |
400 assays |
Ask for price |
Annexin V-iFluor 594 + 7-AAD Apoptosis Detection Reagent |
E34M002D |
EnoGene |
50 rxn |
EUR 225 |
Annexin V-FITC Apoptosis Kit Plus - 400 assays |
GWB-AXR152 |
GenWay Biotech |
400 assays |
Ask for price |
Annexin V-PE Apoptosis Kit Plus - 100 assays |
GWB-AXR156 |
GenWay Biotech |
100 assays |
Ask for price |
Annexin V-PE Apoptosis Kit Plus - 25 assays |
GWB-AXR157 |
GenWay Biotech |
25 assays |
Ask for price |
CaspSCREENTM Flow Cytometric Apoptosis Detection Kit - 100 assays |
GWB-AXR148 |
GenWay Biotech |
100 assays |
Ask for price |
Annexin V-Cy3 Apoptosis Kit - 100 assays |
GWB-AXR004 |
GenWay Biotech |
100 assays |
Ask for price |
Annexin V-Cy5 Apoptosis Kit - 100 assays |
GWB-AXR007 |
GenWay Biotech |
100 assays |
Ask for price |
CaspSCREENTM Flow Cytometric Apoptosis Detection Kit - 25 assays |
GWB-AXR149 |
GenWay Biotech |
25 assays |
Ask for price |
Annexin V-Cy3 Apoptosis Kit - 25 assays |
GWB-AXR005 |
GenWay Biotech |
25 assays |
Ask for price |
Annexin V-Cy5 Apoptosis Kit - 25 assays |
GWB-AXR008 |
GenWay Biotech |
25 assays |
Ask for price |
Annexin V-FITC Apoptosis Kit - 100 assays |
GWB-AXR001 |
GenWay Biotech |
100 assays |
Ask for price |
Annexin V-EGFP Apoptosis Kit - 100 assays |
GWB-AXR010 |
GenWay Biotech |
100 assays |
Ask for price |
Annexin V-FITC Apoptosis Kit - 25 assays |
GWB-AXR002 |
GenWay Biotech |
25 assays |
Ask for price |
Annexin V-EGFP Apoptosis Kit - 25 assays |
GWB-AXR011 |
GenWay Biotech |
25 assays |
Ask for price |
Annexin V-Biotin Apoptosis Kit - 100 assays |
GWB-AXR021 |
GenWay Biotech |
100 assays |
Ask for price |
Annexin V-Biotin Apoptosis Kit - 25 assays |
GWB-AXR022 |
GenWay Biotech |
25 assays |
Ask for price |
Annexin V-Cy3 Apoptosis Kit Plus - 100 assays |
GWB-AXR153 |
GenWay Biotech |
100 assays |
Ask for price |
Annexin V-Cy3 Apoptosis Kit Plus - 25 assays |
GWB-AXR154 |
GenWay Biotech |
25 assays |
Ask for price |
Annexin V-FITC Apoptosis Kit Plus - 100 assays |
GWB-AXR150 |
GenWay Biotech |
100 assays |
Ask for price |
Annexin V-FITC Apoptosis Kit Plus - 25 assays |
GWB-AXR151 |
GenWay Biotech |
25 assays |
Ask for price |
CF®594 TUNEL Assay Apoptosis Detection Kit |
30064-1 |
Biotium |
KT |
EUR 567 |
CF®488A TUNEL Assay Apoptosis Detection Kit |
30063-1 |
Biotium |
KT |
EUR 567 |
CF®640R TUNEL Assay Apoptosis Detection Kit |
30074-1 |
Biotium |
KT |
EUR 567 |
Apoptosis Detection Kit |
ANXVKB-100T |
ImmunoStep |
100 test |
EUR 350.9 |
Description: The kit consists of the AnnexinV conjugated in the selected fluorochrome + solution for the exclusion of nonviable cells (PI) and Binding Buffer |
Apoptosis Detection Kit |
ANXVKCFB-100T |
ImmunoStep |
100 test |
EUR 306.9 |
Description: The kit consists of the AnnexinV conjugated in the selected fluorochrome + solution for the exclusion of nonviable cells (PI) and Binding Buffer |
Apoptosis Detection Kit |
ANXVKCFB7-100T |
ImmunoStep |
100 test |
EUR 306.9 |
Description: The kit consists of the AnnexinV conjugated in the selected fluorochrome + solution for the exclusion of nonviable cells (7AAD) and Binding Buffer |
Apoptosis Detection Kit |
ANXVKDY-100T |
ImmunoStep |
100 test |
EUR 287.1 |
Description: The kit consists of the AnnexinV conjugated in the selected fluorochrome + solution for the exclusion of nonviable cells (PI) and Binding Buffer |
Apoptosis Detection Kit |
ANXVKF-100T |
ImmunoStep |
100 test |
EUR 236.5 |
Description: The kit consists of the AnnexinV conjugated in the selected fluorochrome + solution for the exclusion of nonviable cells (PI) and Binding Buffer |
Apoptosis Detection Kit |
ANXVKF7-100T |
ImmunoStep |
100 test |
EUR 236.5 |
Description: The kit consists of the AnnexinV conjugated in the selected fluorochrome + solution for the exclusion of nonviable cells (7AAD) and Binding Buffer |
Apoptosis Detection Kit |
ANXVKPE-100T |
ImmunoStep |
100 test |
EUR 250.8 |
Description: The kit consists of the AnnexinV conjugated in the selected fluorochrome + solution for the exclusion of nonviable cells (7AAD) and Binding Buffer |
MitoStep + Apoptosis Detection Kit |
KMAF-100T |
ImmunoStep |
100 test |
EUR 313.5 |
Description: Flow Cytometry Mitochondrial Membrane Potencial assay + Apoptosis Detection Kit |
MitoStep + Apoptosis Detection Kit |
KMAPE-100T |
ImmunoStep |
100 test |
EUR 346.5 |
Description: Flow Cytometry Mitochondrial Membrane Potencial assay + Apoptosis Detection Kit |
Our outcomes revealed that DHA induces apoptosis of confluent cells via each intrinsic and extrinsic pathways, which requires activation of p38 MAPK, and includes activation of JNK, caspase-9, caspase-8 and caspase-3 with the exception that cleavage of caspase-Eight was incomplete and truncated BID was not detected on the most time (Eight h) examined. Apoptosis induced by excessive ranges of DHA in wholesome endothelial cells is achieved via constructive suggestions loops linking these MAPKs to a number of caspases, in addition to unfavourable suggestions from p38 MAPK to JNK.