Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

Microplastics (MPs) thought-about as a brand new persistent environmental pollutant may enter into the circulatory system and outcome in lower of sperm amount and high quality in mice. However, the consequences of Polystyrene MPs (PS MPs) on the ovary and its mechanism in rats remained unclear. In this current research, thirty-two wholesome feminine Wistar rats had been uncovered to totally different concentrations of 0.5 µm PS MPs dispersed in deionized water for 90 days. Using hematoxylin-eosin (HE) staining, the quantity of rising follicles was decreased in contrast to the management group.

In addition, the exercise of glutathione peroxidase (GSH-Px), catalase (CAT) and superoxide dismutase (SOD) had been decreased whereas the expression degree of malondialdehyde (MDA) was elevated in ovary tissue. Confirmed by immunohistochemistry, the built-in optical density of NLRP3 and Cleaved-Caspase-1 had been elevated by 13.9 and 14 in granulosa cells in the 1.5 mg/kg/d group. Furthermore, in contrast to the management group, the extent of AMH had been decreased by 23.Three pg/ml whereas IL-1β and IL-18 had been elevated by 32 and 18.5 pg/ml in the 1.5 mg/kg/d group utilizing the enzyme-linked immune sorbent assay (ELISA).

Besides, the apoptosis of granulosa cells was elevated measured by terminal deoxyribonucleotide transferase-mediated nick finish labeling (TUNEL) staining and circulate cytometry. Moreover, western blot assays confirmed that the expressions of NLRP3/Caspase-1 signaling pathway associated elements and Cleaved-Caspase-Three had been elevated. These outcomes demonstrated that PS MPs may induce pyroptosis and apoptosis of ovarian granulosa cells via the NLRP3/Caspase-1 signaling pathway possibly triggered by oxidative stress. The current research prompt that publicity to microplastics had adversarial results on ovary and may very well be a possible danger issue for feminine infertility, which offered new insights into the toxicity of MPs on feminine replica.

The fundamental anthocyanin monomer of Lycium ruthenicum Murray induces apoptosis via the ROS/PTEN/PI3K/Akt/caspase 3 signaling pathway in prostate most cancers DU-145 cells

 

Anthocyanins have been reported to have efficient chemopreventive exercise. Lycium ruthenicum Murray is wealthy in anthocyanins and reveals many organic actions. The objective of this research was to examine the consequences and attainable organic mechanism of the principle anthocyanin monomer (Pt3G) of Lycium ruthenicum Murray on prostate most cancers DU-145 cells. The cell proliferation was detected by methyl thiazolyl tetrazolium assay. The cell apoptosis charges had been assessed by circulate cytometric evaluation and TUNEL assay.

The expressions of apoptosis associated proteins had been evaluated by western blotting. Our knowledge demonstrated that Pt3G inhibited cell proliferation, induced apoptosis and promoted cell cycle arrest on the S section in a concentration-dependent method (0, 100, 200 and 400 μg mL-1). Furthermore, it was proven that Pt3G decreased the mitochondrial membrane permeability via regulating the expressions of Bax and Bcl-2. Western blot evaluation indicated that Pt3G considerably elevated the expression of PTEN and then activated the PI3K/Akt-mediated caspase 3 pathway.

In addition, our outcomes additionally prompt that Pt3G activated the PTEN gene to induce the apoptosis of DU-145 cells by stimulating the overproduction of ROS. To sum up, these outcomes point out that Pt3G inhibits cell proliferation and induces apoptosis via the ROS/PTEN/PI3K/Akt/caspase 3 signaling pathway in prostate most cancers DU-145 cells. Therefore, Pt3G of Lycium ruthenicum Murray could also be a possible anti-proliferative agent for the prevention or therapy of prostate most cancers.

Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

Progesterone induces apoptosis by activation of caspase-8 and calcitriol via activation of caspase-9 pathways in ovarian and endometrial most cancers cells in vitro

 

Previously we’ve proven inhibition of endometrial most cancers cell development with progesterone and calcitriol. However, the mechanisms by which the 2 brokers attenuate proliferation haven’t been properly characterised but. Herein, we investigated how progesterone and calcitriol induce apoptosis in most cancers cells. DNA fragmentation was upregulated by progesterone and calcitriol in ovarian and endometrial most cancers cells.

Time-dependent therapy of ovarian most cancers cells, ES-2, and TOV-21G with progesterone enhanced caspase -Eight exercise after 12 h, whereas OV-90, TOV-112D, HEC-1A, and HEC-59 cells confirmed elevated exercise after 24 h. Caspase 9 exercise was elevated in all cell strains after 24 h therapy with calcitriol. Pretreatment of most cancers cells with a caspase-Eight inhibitor (z-IETD-fmk) or caspase-9 inhibitor (Z-LEHD-fmk) considerably attenuated progesterone and calcitriol induced caspase-8 and caspase-9 expression, respectively. The expression of FasL, Fas, FAD, and pro-caspase-8, which represent the death-inducing signaling complicated (DISC), was upregulated in progesterone handled most cancers cells.

Knockdown of FAS or FADD with particular siRNAs considerably blocked progesterone-induced caspase-8. Cleavage of the BID was not affected by caspase-Eight activation suggesting the absence of cross-talk between caspase-8 and caspase-9 pathways. Calcitriol therapy decreased mitochondrial membrane potential and elevated the discharge of most cancers cytochrome C. These findings point out that progesterone induces apoptosis via activation of caspase-8 and calcitriol via caspase-9 activation in most cancers cells. A mixture of progesterone-calcitriol prompts each extrinsic and intrinsic apoptotic pathways in most cancers cells.

Factor Related Apoptosis (FAS) Antibody

20-abx130850
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Factor Related Apoptosis (FAS) Antibody

20-abx104789
  • EUR 453.00
  • EUR 133.00
  • EUR 1288.00
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  • EUR 342.00
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Factor Related Apoptosis (FAS) Antibody

20-abx102355
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  • EUR 133.00
  • EUR 996.00
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Factor Related Apoptosis (FAS) Antibody

20-abx102356
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  • EUR 133.00
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Factor Related Apoptosis (FAS) Antibody

20-abx102357
  • EUR 356.00
  • EUR 133.00
  • EUR 1024.00
  • EUR 509.00
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Factor Related Apoptosis (FAS) Antibody

20-abx102358
  • EUR 356.00
  • EUR 133.00
  • EUR 1024.00
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Factor Related Apoptosis (FAS) Antibody

20-abx102359
  • EUR 398.00
  • EUR 133.00
  • EUR 1066.00
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Factor Related Apoptosis (FAS) Antibody

20-abx102360
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Factor Related Apoptosis (Fas) Antibody

abx038135-100ug 100 ug
EUR 391
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Factor Related Apoptosis (FAS) Antibody

abx430025-200ul 200 ul
EUR 384
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Factor Related Apoptosis (FAS) Antibody

20-abx270037
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
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Factor Related Apoptosis (FAS) Antibody

20-abx270229
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  • EUR 537.00
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Factor Related Apoptosis (FAS) Antibody

20-abx176352
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Factor Related Apoptosis (FAS) Antibody

20-abx172320
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  • EUR 384.00
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Factor Related Apoptosis (FAS) Antibody

20-abx172321
  • EUR 314.00
  • EUR 773.00
  • EUR 411.00
  • EUR 154.00
  • EUR 258.00
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Factor Related Apoptosis Ligand (FASL) Antibody

20-abx129724
  • EUR 314.00
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  • EUR 829.00
  • EUR 439.00
  • EUR 272.00
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Factor Related Apoptosis (FAS) Antibody Pair

abx117346-1pair5x96wellplates 1 pair (5x96 well plates)
EUR 1010
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Factor Related Apoptosis (FAS) Antibody Pair

20-abx370099
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  • EUR 773.00
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Factor Related Apoptosis Ligand (FASL) Antibody

20-abx103238
  • EUR 314.00
  • EUR 133.00
  • EUR 829.00
  • EUR 439.00
  • EUR 272.00
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Factor Related Apoptosis Ligand (FASL) Antibody

20-abx103239
  • EUR 258.00
  • EUR 133.00
  • EUR 578.00
  • EUR 314.00
  • EUR 230.00
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Factor Related Apoptosis Ligand (FASL) Antibody

20-abx103240
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
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Factor Related Apoptosis Ligand (FASL) Antibody

20-abx103241
  • EUR 467.00
  • EUR 133.00
  • EUR 1372.00
  • EUR 648.00
  • EUR 356.00
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  • Shipped within 5-12 working days.

Factor Related Apoptosis Ligand (FASL) Antibody

20-abx270062
  • EUR 467.00
  • EUR 537.00
  • EUR 272.00
  • EUR 815.00
  • EUR 356.00
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Factor Related Apoptosis Ligand (FASL) Antibody

20-abx270167
  • EUR 467.00
  • EUR 537.00
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Factor Related Apoptosis (FAS) Antibody (FITC)

20-abx270335
  • EUR 523.00
  • EUR 606.00
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  • EUR 940.00
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Factor Related Apoptosis (FAS) Antibody (FITC)

20-abx270527
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Factor Related Apoptosis (FAS) Antibody (APC)

20-abx270567
  • EUR 704.00
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Factor Related Apoptosis (FAS) Antibody (APC)

20-abx270759
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Factor Related Apoptosis (FAS) Antibody (PE)

20-abx270799
  • EUR 606.00
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Factor Related Apoptosis (FAS) Antibody (PE)

20-abx270991
  • EUR 606.00
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  • EUR 439.00
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Factor Related Apoptosis Ligand (FASL) Antibody

20-abx176353
  • EUR 1135.00
  • EUR 551.00
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Factor Related Apoptosis Ligand (FASL) Antibody

20-abx176354
  • EUR 1288.00
  • EUR 620.00
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Factor Related Apoptosis Ligand (FASL) Antibody

20-abx172322
  • EUR 704.00
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Factor Related Apoptosis (FAS) Antibody (FITC)

20-abx273863
  • EUR 411.00
  • EUR 230.00
  • EUR 1163.00
  • EUR 565.00
  • EUR 314.00
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Factor Related Apoptosis (FAS) Antibody (FITC)

20-abx274177
  • EUR 439.00
  • EUR 244.00
  • EUR 1247.00
  • EUR 606.00
  • EUR 328.00
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Factor Related Apoptosis (FAS) Antibody (Biotin)

20-abx271895
  • EUR 398.00
  • EUR 230.00
  • EUR 1080.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
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Factor Related Apoptosis (FAS) Antibody (Biotin)

20-abx272642
  • EUR 398.00
  • EUR 230.00
  • EUR 1107.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
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Factor Related Apoptosis (FAS) Antibody (Biotin)

20-abx273127
  • EUR 411.00
  • EUR 230.00
  • EUR 1163.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Recombinant Factor Related Apoptosis (FAS)

4-RPA030Bo01
  • EUR 556.96
  • EUR 252.00
  • EUR 1813.60
  • EUR 671.20
  • EUR 1242.40
  • EUR 436.00
  • EUR 4384.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P51867
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 30.9kDa
  • Isoelectric Point: Inquire
Description: Recombinant Bovine Factor Related Apoptosis expressed in: E.coli

Recombinant Factor Related Apoptosis (FAS)

4-RPA030Hu01
  • EUR 440.48
  • EUR 221.00
  • EUR 1376.80
  • EUR 525.60
  • EUR 951.20
  • EUR 358.00
  • EUR 3292.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P25445
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 18.2kDa
  • Isoelectric Point: Inquire
Description: Recombinant Human Factor Related Apoptosis expressed in: E.coli

Recombinant Factor Related Apoptosis (FAS)

4-RPA030Hu02
  • EUR 440.48
  • EUR 221.00
  • EUR 1376.80
  • EUR 525.60
  • EUR 951.20
  • EUR 358.00
  • EUR 3292.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P25445
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 48.9kDa
  • Isoelectric Point: Inquire
Description: Recombinant Human Factor Related Apoptosis expressed in: E.coli

Recombinant Factor Related Apoptosis (FAS)

4-RPA030Hu03
  • EUR 440.48
  • EUR 221.00
  • EUR 1376.80
  • EUR 525.60
  • EUR 951.20
  • EUR 358.00
  • EUR 3292.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P25445
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 63.5kDa
  • Isoelectric Point: Inquire
Description: Recombinant Human Factor Related Apoptosis expressed in: E.coli

Recombinant Factor Related Apoptosis (FAS)

4-RPA030Mu01
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P25446
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 20.0kDa
  • Isoelectric Point: 7.8
Description: Recombinant Mouse Factor Related Apoptosis expressed in: E.coli

Recombinant Factor Related Apoptosis (FAS)

4-RPA030Mu02
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P25446
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 16.7kDa
  • Isoelectric Point: Inquire
Description: Recombinant Mouse Factor Related Apoptosis expressed in: E.coli

Recombinant Factor Related Apoptosis (FAS)

4-RPA030Po01
  • EUR 539.04
  • EUR 247.00
  • EUR 1746.40
  • EUR 648.80
  • EUR 1197.60
  • EUR 424.00
  • EUR 4216.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: O77736
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 56.9kDa
  • Isoelectric Point: Inquire
Description: Recombinant Pig Factor Related Apoptosis expressed in: E.coli

Recombinant Factor Related Apoptosis (FAS)

4-RPA030Ra01
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q63199
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 44.0kDa
  • Isoelectric Point: Inquire
Description: Recombinant Rat Factor Related Apoptosis expressed in: E.coli

Recombinant Factor Related Apoptosis (FAS)

4-RPA030Ra02
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q63199
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 48.9kDa
  • Isoelectric Point: 6.2
Description: Recombinant Rat Factor Related Apoptosis expressed in: E.coli

Recombinant Factor Related Apoptosis (FAS)

4-RPA030Ra03
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q63199
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 63.5kDa
  • Isoelectric Point: 5.6
Description: Recombinant Rat Factor Related Apoptosis expressed in: E.coli

Active Factor Related Apoptosis (FAS)

4-APA030Hu03
  • EUR 879.52
  • EUR 338.00
  • EUR 3023.20
  • EUR 1074.40
  • EUR 2048.80
  • EUR 652.00
  • EUR 7408.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P25445
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 66.9kDa
  • Isoelectric Point: 5.8
Description: Recombinant Human Factor Related Apoptosis expressed in: E.coli

Eukaryotic Factor Related Apoptosis (FAS)

4-EPA030Ra61
  • EUR 754.08
  • EUR 305.00
  • EUR 2552.80
  • EUR 917.60
  • EUR 1735.20
  • EUR 568.00
  • EUR 6232.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q63199
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 18.5kDa
  • Isoelectric Point: 6.2
Description: Recombinant Rat Factor Related Apoptosis expressed in: 293F cell

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Factor Related Apoptosis (FAS) Polyclonal Antibody (Bovine)

4-PAA030Bo01
  • EUR 259.00
  • EUR 2694.00
  • EUR 667.00
  • EUR 326.00
  • EUR 218.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Leu37~Tyr274)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Factor Related Apoptosis (FAS)

Factor Related Apoptosis (FAS) Polyclonal Antibody (Human)

4-PAA030Hu01
  • EUR 217.00
  • EUR 2048.00
  • EUR 520.00
  • EUR 268.00
  • EUR 201.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Gln26~Asn173)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Factor Related Apoptosis (FAS)

Factor Related Apoptosis (FAS) Polyclonal Antibody (Human)

4-PAA030Hu02
  • EUR 217.00
  • EUR 2048.00
  • EUR 520.00
  • EUR 268.00
  • EUR 201.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Ser22~Ser172)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Factor Related Apoptosis (FAS)

Factor Related Apoptosis (FAS) Polyclonal Antibody (Human)

4-PAA030Hu03
  • EUR 217.00
  • EUR 2048.00
  • EUR 520.00
  • EUR 268.00
  • EUR 201.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Ser22~Ser172)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Factor Related Apoptosis (FAS)

Factor Related Apoptosis (FAS) Polyclonal Antibody (Mouse)

4-PAA030Mu02
  • EUR 221.00
  • EUR 2100.00
  • EUR 532.00
  • EUR 272.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Lys188~Asn319)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Factor Related Apoptosis (FAS)

Factor Related Apoptosis (FAS) Polyclonal Antibody (Pig)

4-PAA030Po01
  • EUR 259.00
  • EUR 2694.00
  • EUR 667.00
  • EUR 326.00
  • EUR 218.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Glu48~Tyr281)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Pig Factor Related Apoptosis (FAS)

Factor Related Apoptosis (FAS) Polyclonal Antibody (Rat)

4-PAA030Ra01
  • EUR 227.00
  • EUR 2206.00
  • EUR 556.00
  • EUR 282.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Met21~Lys170)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Factor Related Apoptosis (FAS)

Factor Related Apoptosis (FAS) Polyclonal Antibody (Rat)

4-PAA030Ra02
  • EUR 227.00
  • EUR 2206.00
  • EUR 556.00
  • EUR 282.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Met21~Lys170)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Factor Related Apoptosis (FAS)

Factor Related Apoptosis (FAS) Polyclonal Antibody (Rat)

4-PAA030Ra06
  • EUR 240.00
  • EUR 2404.00
  • EUR 601.00
  • EUR 300.00
  • EUR 211.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Gln22~Leu171)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Factor Related Apoptosis (FAS)

Factor Related Apoptosis Ligand (FASL) Antibody Pair

20-abx370039
  • EUR 1177.00
  • EUR 773.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Factor Related Apoptosis Ligand (FASL) Antibody Pair

20-abx370239
  • EUR 1177.00
  • EUR 773.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Factor Related Apoptosis / CD95 / TNFRSF6 (FAS) Antibody

abx412230-50ug 50 ug
EUR 509
  • Shipped within 1 week.

Factor Related Apoptosis Ligand (FASL) Antibody (FITC)

20-abx270360
  • EUR 523.00
  • EUR 606.00
  • EUR 300.00
  • EUR 940.00
  • EUR 384.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests
  • Shipped within 5-15 working days.

Factor Related Apoptosis Ligand (FASL) Antibody (FITC)

20-abx270465
  • EUR 523.00
  • EUR 606.00
  • EUR 300.00
  • EUR 940.00
  • EUR 384.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests
  • Shipped within 5-15 working days.

Factor Related Apoptosis Ligand (FASL) Antibody (APC)

20-abx270592
  • EUR 704.00
  • EUR 829.00
  • EUR 370.00
  • EUR 1330.00
  • EUR 495.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests
  • Shipped within 5-15 working days.

Factor Related Apoptosis Ligand (FASL) Antibody (APC)

20-abx270697
  • EUR 704.00
  • EUR 829.00
  • EUR 370.00
  • EUR 1330.00
  • EUR 495.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests
  • Shipped within 5-15 working days.

Factor Related Apoptosis Ligand (FASL) Antibody (PE)

20-abx270824
  • EUR 606.00
  • EUR 718.00
  • EUR 328.00
  • EUR 1135.00
  • EUR 439.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests
  • Shipped within 5-15 working days.

Factor Related Apoptosis Ligand (FASL) Antibody (PE)

20-abx270929
  • EUR 606.00
  • EUR 718.00
  • EUR 328.00
  • EUR 1135.00
  • EUR 439.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests
  • Shipped within 5-15 working days.

Factor Related Apoptosis Ligand / TNFSF6 (FASLG) Antibody

abx233016-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Factor Related Apoptosis Ligand / TNFSF6 (FASLG) Antibody

abx233017-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Factor Related Apoptosis Ligand (FASL) Antibody (FITC)

20-abx274189
  • EUR 523.00
  • EUR 258.00
  • EUR 1609.00
  • EUR 746.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Factor Related Apoptosis Ligand (FASL) Antibody (Biotin)

20-abx271896
  • EUR 328.00
  • EUR 217.00
  • EUR 899.00
  • EUR 453.00
  • EUR 286.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Factor Related Apoptosis Ligand (FASL) Antibody (Biotin)

20-abx273435
  • EUR 495.00
  • EUR 258.00
  • EUR 1497.00
  • EUR 704.00
  • EUR 398.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Recombinant Factor Related Apoptosis Ligand (FASL)

4-RPA031Hu01
  • EUR 481.70
  • EUR 232.00
  • EUR 1531.36
  • EUR 577.12
  • EUR 1054.24
  • EUR 385.00
  • EUR 3678.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P48023
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 52.4kDa
  • Isoelectric Point: Inquire
Description: Recombinant Human Factor Related Apoptosis Ligand expressed in: E.coli

Recombinant Factor Related Apoptosis Ligand (FASL)

4-RPA031Hu02
  • EUR 481.70
  • EUR 232.00
  • EUR 1531.36
  • EUR 577.12
  • EUR 1054.24
  • EUR 385.00
  • EUR 3678.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P48023
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 14.3kDa
  • Isoelectric Point: Inquire
Description: Recombinant Human Factor Related Apoptosis Ligand expressed in: E.coli

Recombinant Factor Related Apoptosis Ligand (FASL)

4-RPA031Mu01
  • EUR 440.48
  • EUR 221.00
  • EUR 1376.80
  • EUR 525.60
  • EUR 951.20
  • EUR 358.00
  • EUR 3292.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q544E9
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 49.3kDa
  • Isoelectric Point: 7
Description: Recombinant Mouse Factor Related Apoptosis Ligand expressed in: E.coli

Recombinant Factor Related Apoptosis Ligand (FASL)

4-RPA031Ra01
  • EUR 508.58
  • EUR 239.00
  • EUR 1632.16
  • EUR 610.72
  • EUR 1121.44
  • EUR 403.00
  • EUR 3930.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P36940
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 52.2kDa
  • Isoelectric Point: 7.7
Description: Recombinant Rat Factor Related Apoptosis Ligand expressed in: E.coli

Recombinant Factor Related Apoptosis Ligand (FASL)

4-RPA031Si01
  • EUR 539.04
  • EUR 247.00
  • EUR 1746.40
  • EUR 648.80
  • EUR 1197.60
  • EUR 424.00
  • EUR 4216.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P63307
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 21.7kDa
  • Isoelectric Point: Inquire
Description: Recombinant Simian Factor Related Apoptosis Ligand expressed in: E.coli

Rat Factor Related Apoptosis (FAS) Protein

20-abx651484
  • EUR 1038.00
  • EUR 356.00
  • EUR 3418.00
  • EUR 1247.00
  • EUR 704.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Monkey Factor Related Apoptosis (FAS) Protein

20-abx653333
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Human Factor Related Apoptosis (FAS) Protein

20-abx066477
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Mouse Factor Related Apoptosis (FAS) Protein

20-abx066478
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Rat Factor Related Apoptosis (FAS) Protein

20-abx066479
  • EUR 732.00
  • EUR 286.00
  • EUR 2305.00
  • EUR 885.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Mouse Factor Related Apoptosis (FAS) Protein

20-abx066480
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Rat Factor Related Apoptosis (FAS) Protein

20-abx066481
  • EUR 732.00
  • EUR 286.00
  • EUR 2305.00
  • EUR 885.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Human Factor Related Apoptosis (FAS) Protein

20-abx066482
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Rat Factor Related Apoptosis (FAS) Protein

20-abx066483
  • EUR 732.00
  • EUR 286.00
  • EUR 2305.00
  • EUR 885.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Human Factor Related Apoptosis (FAS) Protein

20-abx166447
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Pig Factor Related Apoptosis (FAS) Protein

20-abx167536
  • EUR 746.00
  • EUR 300.00
  • EUR 2346.00
  • EUR 899.00
  • EUR 537.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Cow Factor Related Apoptosis (FAS) Protein

20-abx168020
  • EUR 773.00
  • EUR 300.00
  • EUR 2444.00
  • EUR 926.00
  • EUR 551.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Porcine Factor- related Apoptosis ELISA Kit

ELA-E0030p 96 Tests
EUR 928

Factor Related Apoptosis (FAS) Polyclonal Antibody (Bovine), APC

4-PAA030Bo01-APC
  • EUR 363.00
  • EUR 3527.00
  • EUR 975.00
  • EUR 465.00
  • EUR 226.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Leu37~Tyr274)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Factor Related Apoptosis (FAS). This antibody is labeled with APC.

Factor Related Apoptosis (FAS) Polyclonal Antibody (Bovine), Biotinylated

4-PAA030Bo01-Biotin
  • EUR 324.00
  • EUR 2644.00
  • EUR 773.00
  • EUR 399.00
  • EUR 224.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Leu37~Tyr274)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Factor Related Apoptosis (FAS). This antibody is labeled with Biotin.

Factor Related Apoptosis (FAS) Polyclonal Antibody (Bovine), Cy3

4-PAA030Bo01-Cy3
  • EUR 443.00
  • EUR 4661.00
  • EUR 1259.00
  • EUR 578.00
  • EUR 260.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Leu37~Tyr274)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Factor Related Apoptosis (FAS). This antibody is labeled with Cy3.

Factor Related Apoptosis (FAS) Polyclonal Antibody (Bovine), FITC

4-PAA030Bo01-FITC
  • EUR 310.00
  • EUR 2841.00
  • EUR 800.00
  • EUR 392.00
  • EUR 201.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Leu37~Tyr274)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Factor Related Apoptosis (FAS). This antibody is labeled with FITC.

Factor Related Apoptosis (FAS) Polyclonal Antibody (Bovine), HRP

4-PAA030Bo01-HRP
  • EUR 331.00
  • EUR 3073.00
  • EUR 862.00
  • EUR 419.00
  • EUR 213.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: FAS (Leu37~Tyr274)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Bovine Factor Related Apoptosis (FAS). This antibody is labeled with HRP.

Deoxynivalenol (DON) is a typical trichothecene mycotoxin discovered worldwide. DON has broad toxicity in direction of animals and people. However, the mechanism of DON-induced neurotoxicity in vitro has not been absolutely understood. This research investigated the speculation that DON toxicity in neurons happens via the mitochondrial apoptotic pathway. Using piglet hippocampal nerve cells (PHNCs), we evaluated the consequences of totally different concentrations of DON on typical indicators of apoptosis.